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Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. A cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the BMK cascade. A cascade of protein kinase activities, culminating in the phosphorylation and activation of big MAP kinase (BMK1/ERK5), which is a type of mitogen-activated protein (MAP) kinase. Any process that modulates the frequency, rate or extent of signal transduction mediated by the BMK cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of BMK cascade
Acc: GO:0070378
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the BMK cascade.
Synonyms:
  • positive regulation of ERK5 cascade
  • positive regulation of BMK signaling pathway
  • positive regulation of ERK5 signaling pathway
  • positive regulation of BMK1 cascade
  • upregulation of BMK cascade
  • activation of BMK cascade
  • positive regulation of MAPK7 cascade
  • up regulation of BMK cascade
  • positive regulation of BMK signalling pathway
  • stimulation of BMK cascade
  • up-regulation of BMK cascade
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070378 - positive regulation of BMK cascade (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle