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Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell. A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. Any process that stops, prevents or reduces the frequency, rate or extent of a signaling process. The process whereby a signal is released and/or conveyed from one location to another. Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction via a two-component phosphorelay signal transduction system. Any process that modulates the frequency, rate or extent of signal transduction via a two-component phosphorelay signal transduction system. Any process that stops or prevents ethylene (ethene) mediated signaling. Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction. Any process that modulates the frequency, rate or extent of signal transduction.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of two-component signal transduction system (phosphorelay)
Acc: GO:0070298
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction via a two-component phosphorelay signal transduction system.
Synonyms:
  • down regulation of two-component signal transduction
  • downregulation of two-component signal transduction
  • negative regulation of histidyl-aspartyl phosphorelay
  • down-regulation of two-component signal transduction
  • negative regulation of two-component signal transduction system (phosphorelay)
  • inhibition of two-component signal transduction
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070298 - negative regulation of two-component signal transduction system (phosphorelay) (interactive image map)
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