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The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands. The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate. The process whereby a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment
Acc: GO:0060851
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060851 - vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle