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Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. Any process involved in forming the mature 3' end of an mRNA molecule. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA processing. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-end processing. Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule. Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
Acc: GO:0060212
Aspect: Biological Process
Desc: Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
Synonyms:
  • negative regulation of 3' to 5' mRNA deadenylation
  • negative regulation of mRNA deadenylation
  • negative regulation of nuclear mRNA poly(A) tail shortening
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060212 - negative regulation of nuclear-transcribed mRNA poly(A) tail shortening (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle