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Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. Any process that prevents the activation of the directed movement of serotonin into a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of serotonin into a cell. The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. It does not occur during cholinergic synaptic transmission. Instead, acetylcholine is enzymatically degraded in the synaptic cleft. Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell. The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of serotonin into, out of, within or between cells by means of some external agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of serotonin uptake
Acc: GO:0051612
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.
Synonyms:
  • negative regulation of 5HT uptake
  • negative regulation of 5-HT uptake
  • negative regulation of 5-hydroxytryptamine uptake
  • negative regulation of serotonin import
  • down regulation of serotonin uptake
  • down-regulation of serotonin uptake
  • downregulation of serotonin uptake
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051612 - negative regulation of serotonin uptake (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle