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The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. The 'de novo' formation of a microtubule, mediated by the spindle pole body. The 'de novo' formation of a microtubule, mediated by the microtubule organizing center. The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: microtubule nucleation by microtubule organizing center
Acc: GO:0051418
Aspect: Biological Process
Desc: The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.
Synonyms:
  • microtubule nucleation by microtubule organising centre
  • MTOC-mediated microtubule nucleation
  • microtubule organizing center-mediated microtubule nucleation
  • microtubule nucleation by MTOC
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051418 - microtubule nucleation by microtubule organizing center (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle