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Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Any process that modulates the frequency, rate or extent of protein kinase activity. A cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. Any process that terminates the activity of the active enzyme MAP kinase kinase kinase. Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase activity. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inactivation of MAPKKK activity
Acc: GO:0051390
Aspect: Biological Process
Desc: Any process that terminates the activity of the active enzyme MAP kinase kinase kinase.
Synonyms:
  • inactivation of MAP kinase kinase kinase activity
  • termination of MAPKKK activity
  • termination of MAP kinase kinase kinase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051390 - inactivation of MAPKKK activity (interactive image map)
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