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Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. Any process that activates or increases the activity of an enzyme. Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of cyclic-nucleotide phosphodiesterase activity
Acc: GO:0051343
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms:
  • activation of cyclic nucleotide phosphodiesterase activity
  • up-regulation of cyclic nucleotide phosphodiesterase activity
  • upregulation of cyclic nucleotide phosphodiesterase activity
  • positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity
  • 3',5'-cyclic-AMP phosphodiesterase activator
  • stimulation of cyclic nucleotide phosphodiesterase activity
  • positive regulation of cyclic nucleotide phosphodiesterase activity
  • cAMP phosphodiesterase activator
  • up regulation of cyclic nucleotide phosphodiesterase activity
  • positive regulation of cGMP phosphodiesterase activity
  • positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity
  • phosphodiesterase activator
  • positive regulation of cAMP phosphodiesterase activity
  • 3',5' cyclic nucleotide phosphodiesterase activator
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051343 - positive regulation of cyclic-nucleotide phosphodiesterase activity (interactive image map)
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