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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments. The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. The chemical reactions and pathways by which individual cells transform chemical substances. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: prosthetic group metabolic process
Acc: GO:0051189
Aspect: Biological Process
Desc: The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
Synonyms:
  • coenzyme and prosthetic group metabolism
  • coenzyme and prosthetic group metabolic process
  • prosthetic group metabolism
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 142 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051189 - prosthetic group metabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle