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The process by which a fluid solution, or part of it, changes into a solid or semisolid mass. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process by which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response. Any process that stops, prevents or reduces the frequency, rate or extent of coagulation. Any biological process, occurring at the level of a multicellular organism, pertinent to its function. Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass. The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Any process that activates or increases the frequency, rate or extent of coagulation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: coagulation
Acc: GO:0050817
Aspect: Biological Process
Desc: The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
Synonyms:
  • clotting
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 572 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050817 - coagulation (interactive image map)
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