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Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. Any process that stops, prevents or reduces the frequency, rate or extent of the proliferation of neuroblasts. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons. A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. Any process that stops, prevents or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons. Any process that stops, prevents or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. Any process that stops, prevents or reduces the frequency, rate or extent of dendrite morphogenesis. Any process that stops, prevents or reduces the frequency, rate or extent of axonogenesis. The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. Generation of cells within the nervous system.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of neurogenesis
Acc: GO:0050768
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
Synonyms:
  • down-regulation of neurogenesis
  • down regulation of neurogenesis
  • downregulation of neurogenesis
  • inhibition of neurogenesis
Proteins in PDR annotated with:
   This term: 22 [Search]
   Term or descendants: 157 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050768 - negative regulation of neurogenesis (interactive image map)
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Created and Maintained by: Michael Riffle