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Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tryptophan 2'-dioxygenase activity
Acc: GO:0050360
Aspect: Molecular Function
Desc: Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.
Synonyms:
  • tryptophan side-chain oxidase activity
  • L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)
  • tryptophan side-chain alpha,beta-oxidase activity
  • tryptophan side chain oxidase type I
  • tryptophan side chain oxidase activity
  • tryptophan side chain oxidase II
  • indole-3-alkane alpha-hydroxylase activity
  • TSO activity
  • TSO II
  • indolyl-3-alkan alpha-hydroxylase activity
  • TSO I
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050360 - tryptophan 2'-dioxygenase activity (interactive image map)
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