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Any process that stops, prevents or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination. Process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Any process that stops, prevents or reduces the frequency, rate or extent of axial mesoderm cell fate determination. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The process by which a cell becomes committed to become part of the mesoderm. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Any process that stops, prevents or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination. Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. Any process that stops, prevents or reduces the frequency, rate or extent of lateral mesoderm cell fate determination. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that modulates the frequency, rate or extent of mesoderm cell fate determination. Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate determination. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of mesodermal cell fate determination
Acc: GO:0048335
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate determination.
Synonyms:
  • down-regulation of mesodermal cell fate determination
  • inhibition of mesodermal cell fate determination
  • downregulation of mesodermal cell fate determination
  • down regulation of mesodermal cell fate determination
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048335 - negative regulation of mesodermal cell fate determination (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle