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Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: trypanothione synthase activity
Acc: GO:0047479
Aspect: Molecular Function
Desc: Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.
Synonyms:
  • glutathionylspermidine:glutathione ligase (ADP-forming)
  • TSR synthetase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047479 - trypanothione synthase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle