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Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. Any process that stops, prevents, or reduces the rate of leukocyte degranulation. Any process that modulates the frequency, rate, or extent of leukocyte degranulation. The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. Any process that modulates the frequency, rate or extent of natural killer cell activation. The regulated exocytosis of secretory granules by a leukocyte. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. Any process that stops, prevents or reduces the frequency, rate or extent of exocytosis. The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation. The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of natural killer cell degranulation
Acc: GO:0043322
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.
Synonyms:
  • downregulation of natural killer cell degranulation
  • negative regulation of NK cell degranulation
  • down regulation of natural killer cell degranulation
  • negative regulation of NK cell granule exocytosis
  • down-regulation of natural killer cell degranulation
  • negative regulation of natural killer cell granule exocytosis
  • inhibition of natural killer cell degranulation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043322 - negative regulation of natural killer cell degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle