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The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. Any process that modulates the frequency, rate or extent of T cell activation. Any process that modulates the frequency, rate, or extent of leukocyte degranulation. Any process that activates or increases the frequency, rate or extent of lymphocyte activation. Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation. The regulated exocytosis of secretory granules by a leukocyte. Any process that activates or increases the frequency, rate, or extent of an immune effector process. Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation. Any process that activates or increases the frequency, rate or extent of exocytosis. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity. The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. Any process that activates or increases the frequency, rate or extent of T cell activation. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of cytotoxic T cell degranulation
Acc: GO:0043319
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.
Synonyms:
  • positive regulation of cytotoxic T cell granule exocytosis
  • positive regulation of cytotoxic T lymphocyte granule exocytosis
  • positive regulation of cytotoxic T-cell degranulation
  • up regulation of cytotoxic T cell degranulation
  • positive regulation of cytotoxic T lymphocyte degranulation
  • positive regulation of cytotoxic T-cell granule exocytosis
  • upregulation of cytotoxic T cell degranulation
  • positive regulation of cytotoxic T-lymphocyte degranulation
  • up-regulation of cytotoxic T cell degranulation
  • positive regulation of cytotoxic T-lymphocyte granule exocytosis
  • activation of cytotoxic T cell degranulation
  • stimulation of cytotoxic T cell degranulation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043319 - positive regulation of cytotoxic T cell degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle