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The union of male and female gametes to form a zygote. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane. Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane. The joining of two or more lipid bilayer membranes that surround a cell. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of fusion of sperm to egg plasma membrane
Acc: GO:0043013
Aspect: Biological Process
Desc: Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.
Synonyms:
  • downregulation of fusion of sperm to egg plasma membrane
  • inhibition of fusion of sperm to egg plasma membrane
  • down regulation of fusion of sperm to egg plasma membrane
  • down-regulation of fusion of sperm to egg plasma membrane
  • negative regulation of sperm-oocyte fusion
  • inhibition of sperm-oocyte fusion
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043013 - negative regulation of fusion of sperm to egg plasma membrane (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle