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Any process that stops, prevents or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane. Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. Any process that stops, prevents or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. Any process by which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cytoplasmic sequestering of CFTR protein
Acc: GO:0043004
Aspect: Biological Process
Desc: The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane.
Synonyms:
  • sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm
  • storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm
  • maintenance of CFTR protein location in cytoplasm
  • cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)
  • cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein
  • cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein
  • sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm
  • retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm
  • cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043004 - cytoplasmic sequestering of CFTR protein (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle