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The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. The process of introducing a phosphate group to a tyrosine residue of a Stat1 protein. Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein. Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein. The posttranslational phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein. Any process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tyrosine phosphorylation of Stat1 protein
Acc: GO:0042508
Aspect: Biological Process
Desc: The process of introducing a phosphate group to a tyrosine residue of a Stat1 protein.
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042508 - tyrosine phosphorylation of Stat1 protein (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle