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The process whereby a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. The addition a sulfur atom to a nucleotide in a tRNA molecule. The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule. The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: tRNA thio-modification
Acc: GO:0034227
Aspect: Biological Process
Desc: The addition a sulfur atom to a nucleotide in a tRNA molecule.
Synonyms:
  • tRNA sulfurtransferase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034227 - tRNA thio-modification (interactive image map)

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