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The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production. The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. Any process that modulates the frequency, rate, or extent of tumor necrosis factor production. Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tumor necrosis factor production
Acc: GO:0032640
Aspect: Biological Process
Desc: The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:
  • TNF-alpha production
  • TNF production
  • tumor necrosis factor-alpha production
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 76 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032640 - tumor necrosis factor production (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle