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The process by which the migration of an axon growth cone is directed to a specific target site in response to a combination of attractive and repulsive cues. Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline. The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth. The process by which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side. The process by which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: corticospinal neuron axon decussation
Acc: GO:0021973
Aspect: Biological Process
Desc: The process by which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0021973 - corticospinal neuron axon decussation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle