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The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing. The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing. The post-translational removal of peptide sequences from within a protein sequence. Any protein maturation process achieved by the cleavage of peptide bonds. The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: intein-mediated protein splicing
Acc: GO:0016539
Aspect: Biological Process
Desc: The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.
Synonyms:
  • intein
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 21 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016539 - intein-mediated protein splicing (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle