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Any process that stops, prevents or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. The process whereby a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. Any process that stops, prevents or reduces the frequency, rate or extent of glia cell differentiation. Any process that modulates the frequency, rate or extent of glia cell differentiation. The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell. Any process that stops, prevents or reduces the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell. Any process that modulates the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell. The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of microglia differentiation
Acc: GO:0014007
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell.
Synonyms:
  • down regulation of microglia differentiation
  • down-regulation of microglia differentiation
  • downregulation of microglia differentiation
  • inhibition of microglia differentiation
  • negative regulation of microglial cell differentiation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014007 - negative regulation of microglia differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle