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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that modulates the frequency, rate or extent of a signaling pathway. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. Any process that stops, prevents or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of platelet-derived growth factor receptor signaling pathway
Acc: GO:0010642
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
Synonyms:
  • negative regulation of platelet-derived growth factor receptor signalling pathway
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010642 - negative regulation of platelet-derived growth factor receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle