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Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. Catalysis of the reaction: acetyl-CoA + H2O = CoA + acetate. Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: acetyl-CoA hydrolase activity
Acc: GO:0003986
Aspect: Molecular Function
Desc: Catalysis of the reaction: acetyl-CoA + H2O = CoA + acetate.
Synonyms:
  • acetyl coenzyme A hydrolase activity
  • acetyl coenzyme A acylase activity
  • acetyl-CoA deacylase activity
  • acetyl coenzyme A deacylase activity
  • acetyl-CoA acylase activity
  • acetyl-CoA thiol esterase activity
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003986 - acetyl-CoA hydrolase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle