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Tolerance induction in response to nonself antigens. Tolerance induction to nonself antigens in the central lymphoid organs. Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. Tolerance induction in the central lymphoid organs: the thymus and bone marrow. A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: central tolerance induction to nonself antigen
Acc: GO:0002463
Aspect: Biological Process
Desc: Tolerance induction to nonself antigens in the central lymphoid organs.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002463 - central tolerance induction to nonself antigen (interactive image map)
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Created and Maintained by: Michael Riffle