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The process whereby immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent. The process whereby immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21. The process whereby immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a precursor cell type acquires the specialized features of an immature B cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transitional stage B cell differentiation
Acc: GO:0002332
Aspect: Biological Process
Desc: The process whereby immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.
Synonyms:
  • transitional stage B-cell differentiation
  • transitional stage B-lymphocyte differentiation
  • transitional stage B lymphocyte differentiation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002332 - transitional stage B cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle