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Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Any process that modulates the frequency, rate or extent of complement activation. Any process that modulates the rate, frequency or extent of protein maturation by peptide bond cleavage. The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. Any process that stops, prevents or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. Any process that modulates the frequency, rate, or extent of a humoral immune response. Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. Any process that modulates the frequency, rate, or extent of an acute inflammatory response. Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. Any process that modulates the frequency, rate, or extent of an immune effector process.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of activation of membrane attack complex
Acc: GO:0001969
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms:
  • regulation of MAC formation
  • regulation of membrane attack complex assembly
  • regulation of membrane attack complex formation
  • regulation of MAC assembly
  • regulation of activation of TCC
  • regulation of activation of MAC
  • regulation of activation of the terminal complement cascade
  • regulation of activation of terminal complement complex
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001969 - regulation of activation of membrane attack complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle