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Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation. Any process that modulates the frequency, rate or extent of B cell differentiation. Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. The process whereby transitional stage B cells acquire the specialized features of mature B cells in the spleen. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of B-1 B cell differentiation
Acc: GO:0001925
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.
Synonyms:
  • downregulation of B-1 B cell differentiation
  • inhibition of B-1 B cell differentiation
  • negative regulation of B-1 B-lymphocyte differentiation
  • down-regulation of B-1 B cell differentiation
  • down regulation of B-1 B cell differentiation
  • negative regulation of B-1 B-cell differentiation
  • negative regulation of B-1 B lymphocyte differentiation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001925 - negative regulation of B-1 B cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle