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Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity. An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell. A process that directly activates any of the steps required for cell death by apoptosis. Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. The directed killing of a target cell by a leukocyte. Any process that stops, prevents or reduces the frequency, rate or extent of cell killing. Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response. Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response. Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells. Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of antibody-dependent cellular cytotoxicity
Acc: GO:0001814
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.
Synonyms:
  • down-regulation of antibody-dependent cellular cytotoxicity
  • negative regulation of antibody-dependent cell killing
  • downregulation of antibody-dependent cellular cytotoxicity
  • negative regulation of antibody dependent cell killing
  • negative regulation of antibody dependent cell death
  • down regulation of antibody-dependent cellular cytotoxicity
  • inhibition of antibody-dependent cellular cytotoxicity
  • negative regulation of antibody-dependent cell death
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001814 - negative regulation of antibody-dependent cellular cytotoxicity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle