GO TERM SUMMARY
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Name: |
extrachromosomal rDNA circle accumulation involved in replicative cell aging |
Acc: |
GO:0001310 |
Aspect: |
Biological Process |
Desc: |
Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. |
Synonyms:
- extrachromosomal rDNA circle accumulation during replicative cell ageing
- extrachromosomal ribosomal DNA circle accumulation during replicative cell aging
- extrachromosomal rDNA circle accumulation during replicative cell aging
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