Abstract
A Caenorhabditis elegans cDNA for a glutamate transporter was cloned and examined in this study. The predicted protein is 11 residues shorter at the N-terminus than Ceglut-1, which we previously reported. The protein, when expressed in Xenopus laevis oocytes, showed much higher glutamate transport activity than Ceglut-1, suggesting that the N-terminal sequence is critical in glutamate transport.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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ATP-Binding Cassette Transporters / chemistry*
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ATP-Binding Cassette Transporters / physiology
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Amino Acid Sequence
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Amino Acid Transport System X-AG
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Animals
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Base Sequence
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Biological Transport / physiology
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Caenorhabditis elegans / metabolism*
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Cloning, Molecular
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Molecular Sequence Data
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Oocytes / metabolism
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Recombinant Proteins / biosynthesis
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Structure-Activity Relationship
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Xenopus laevis
Substances
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ATP-Binding Cassette Transporters
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Amino Acid Transport System X-AG
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Recombinant Proteins
Associated data
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GENBANK/D86741
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GENBANK/U51998