Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe

Yeast. 1995 Sep 30;11(12):1171-7. doi: 10.1002/yea.320111207.

Abstract

By complementation of a mutant resistant to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative gamma-glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Genes, Fungal*
  • Glutamate-Cysteine Ligase / chemistry
  • Glutamate-Cysteine Ligase / genetics*
  • Introns
  • Molecular Sequence Data
  • Schizosaccharomyces / enzymology
  • Schizosaccharomyces / genetics*

Substances

  • Glutamate-Cysteine Ligase

Associated data

  • GENBANK/X85017