Abstract
The process of meiosis reduces a diploid cell to four haploid gametes and is accompanied by extensive recombination. Thus, chromosome dynamics in meiosis are significantly different than in mitotic cells. This review analyzes unique features of meiotic DNA replication and describes how it affects subsequent recombination and chromosome segregation.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cell Cycle Proteins / physiology
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Chromatids / physiology
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Chromosomal Proteins, Non-Histone
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Chromosome Segregation / physiology*
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Chromosomes / genetics
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Chromosomes / physiology
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Chromosomes, Fungal / genetics
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Chromosomes, Fungal / physiology
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Cohesins
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DNA Replication / physiology*
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Fungal Proteins
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Genes, cdc
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Meiosis / genetics*
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Mitosis
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Models, Genetic
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Nuclear Proteins / physiology
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Phosphoproteins*
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Recombination, Genetic
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Replication Origin
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S Phase
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Saccharomyces cerevisiae / cytology
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae Proteins / physiology
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Schizosaccharomyces / cytology
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Schizosaccharomyces / genetics
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Schizosaccharomyces pombe Proteins / physiology
Substances
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Cell Cycle Proteins
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Chromosomal Proteins, Non-Histone
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Fungal Proteins
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MCD1 protein, S cerevisiae
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Nuclear Proteins
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Phosphoproteins
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Saccharomyces cerevisiae Proteins
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Schizosaccharomyces pombe Proteins
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REC8 protein, S pombe