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Protein Overview: AAP1

General Information:
Name(s) found: AAP1 / YHR047C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 856 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: glycogen metabolic process [IMPLink to PubMed article]
    proteolysis [IMPLink to PubMed article]
    Molecular Function: aminopeptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSREVLPNNV TPLHYDITLE PNFRAFTFEG SLKIDLQIND HSINSVQINY LEIDFHSARI  60
   61 EGVNAIEVNK NENQQKATLV FPNGTFENLG PSAKLEIIFS GILNDQMAGF YRAKYTDKVT 120
  121 GETKYMATTQ MEATDARRAF PCFDEPNLKA TFAVTLVSES FLTHLSNMDV RNETIKEGKK 180
  181 YTTFNTTPKM STYLVAFIVA DLRYVESNNF RIPVRVYSTP GDEKFGQFAA NLAARTLRFF 240
  241 EDTFNIEYPL PKMDMVAVHE FSAGAMENWG LVTYRVIDLL LDIENSSLDR IQRVAEVIQH 300
  301 ELAHQWFGNL VTMDWWEGLW LNEGFATWMS WYSCNKFQPE WKVWEQYVTD NLQRALNLDS 360
  361 LRSSHPIEVP VNNADEINQI FDAISYSKGS SLLRMISKWL GEETFIKGVS QYLNKFKYGN 420
  421 AKTGDLWDAL ADASGKDVCS VMNIWTKRVG FPVLSVKEHK NKITLTQHRY LSTGDVKEEE 480
  481 DTTIYPILLA LKDSTGIDNT LVLNEKSATF ELKNEEFFKI NGDQSGIFIT SYSDERWAKL 540
  541 SKQANLLSVE DRVGLVADAK ALSASGYTST TNFLNLISNW KNEDSFVVWE QIINSLSALK 600
  601 STWVFEPEDI LNALDKFTLD LVLNKLSELG WNIGEDDSFA IQRLKVTLFS AACTSGNEKM 660
  661 QSIAVEMFEE YANGNKQAIP ALFKAVVFNT VARLGGENNY EKIFNIYQNP VSSEEKIIAL 720
  721 RALGRFEDKE LLERTLSYLL DGTVLNQDFY IPMQGIRVHK KGIERLWAWM QEHWDEIAKR 780
  781 LQPGSPVLGG VLTLGLTNFT SFEALEKISA FYSRKVTKGF DQTLAQALDT IRSKAQWVSR 840
  841 DREIVATYLR EHEYDQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AAP1 GUD1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AAP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 239.06601 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
    2 View Details [206..298] PSI-BLAST 239.06601 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
    3 View Details [299..475] PSI-BLAST 239.06601 Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
    4 View Details [476..598] ORFEUS 11.39 Adaptin beta subunit N-terminal fragment
    5 View Details [599..696] ORFEUS 11.39 Adaptin beta subunit N-terminal fragment
    6 View Details [697..856] ORFEUS 11.39 Adaptin beta subunit N-terminal fragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle