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Protein Overview: DUR3

General Information:
Name(s) found: DUR3 / YHL016C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 735 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: urea transport [IMPLink to PubMed article][ISSLink to PubMed article]
    spermidine transport [IDALink to PubMed article][IMPLink to PubMed article]
    putrescine transport [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: putrescine transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]
    spermidine transmembrane transporter activity [IDALink to PubMed article][IMPLink to PubMed article]
    urea transmembrane transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEFKPPLPQ GAGYAIVLGL GAVFAGMMVL TTYLLKRYQK EIITAEEFTT AGRSVKTGLV  60
   61 AAAVVSSWIW CSTLLTSSTK EYADGIFGGY AYAAGACFQI IAFAILAIKT KQMAPNAHTY 120
  121 LELVRTRYGK IGHGCYLFYA IATNILVTSM LLTSGSAVFS DLTGMNTIAS CFLLPVGVVV 180
  181 YTLFGGIKAT FLTDYMHTCV IIIIVLVFAF KVYATSDVLG SPGKVYDLVR EAAKRHPVDG 240
  241 NYQGEYMTMT SKSAGILLII NLIGNFGTVF LDNGYWNKAI SASPAASLKA YAIGGLAWFA 300
  301 VPSLISLTMG LACLAVETSP NFPTYPDPLT SFQANSGLVL PAAAIAIMGK GGAVASLLMI 360
  361 FMAVTSAMSA ELIAVSSVFT YDIYREYIDP RASGKKLIYT SHVACIFFGL AMSGFSVGLY 420
  421 YGGISMGYIY EMMGIIISSA VLPVVLTLCS KDMNLVAAVV SPILGTGLAI MSWLVCTKSL 480
  481 YKELTVDTTF MDYPMLTGNL VALLSPAIFI PILTYVFKPQ NFDWEKMKDI TRVDETAELV 540
  541 QADPDIQLYD AEANDKEQEE ETNSLVSDSE KNDVRVNNEK LIEPNLGVVI SNAIFQEDDT 600
  601 QLQNELDEEQ RELARGLKIA YFLCVFFALA FLVVWPMPMY GSKYIFSKKF FTGWVVVMII 660
  661 WLFFSAFAVC IYPLWEGRHG IYTTLRGLYW DLSGQTYKLR EWQNSNPQDL HVVTSQISAR 720
  721 AHRQSSHFGQ VDEII

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AAC3 AGP3 AST2 DUR3 GAP1 RTA1 SAM3 TPO3 YLR326W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..486] Pfam 5.0 Sodium:solute symporter family No confident structure predictions are available.
    2 View Details [487..577] MSA 2.177991 View MSA. No confident structure predictions are available.
    3 View Details [578..648] MSA 1.030989 View MSA. No confident structure predictions are available.
    4 View Details [649..735] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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