General Information: |
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Name(s) found: |
SPHK1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 383 amino acids |
Gene Ontology: |
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Cellular Component: |
membrane fraction
[UNKNOWN]
soluble fraction [UNKNOWN] cytoplasm [UNKNOWN] synaptic vesicle [IDA] cytosol [UNKNOWN][IDA] neuron projection [IDA] plasma membrane [IDA] axon [IDA] |
Biological Process: |
positive regulation of cell proliferation
[UNKNOWN]
response to progesterone stimulus [IEP] positive regulation of angiogenesis [UNKNOWN] positive regulation of smooth muscle contraction [UNKNOWN] inflammatory response [UNKNOWN] positive regulation of cell growth [UNKNOWN] blood vessel development [UNKNOWN] positive regulation of fibroblast proliferation [UNKNOWN] response to magnesium ion [IEP] positive regulation of neuron projection development [IMP] cellular response to hydrogen peroxide [IEP] calcium-mediated signaling [UNKNOWN] response to protein stimulus [IEP] response to ATP [IEP] response to amine stimulus [IEP] female pregnancy [IEP] brain development [UNKNOWN] cellular response to starvation [IEP] response to organic cyclic substance [IEP] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEA] positive regulation of mitotic cell cycle [UNKNOWN] cyclooxygenase pathway [IDA] negative regulation of apoptosis [IMP] positive regulation of protein amino acid phosphorylation [IMP] positive regulation of neurotransmitter secretion [IMP] response to interleukin-1 [IEP] regulation of interleukin-1 beta production [UNKNOWN] positive regulation of cell migration [UNKNOWN][IMP] |
Molecular Function: |
magnesium ion binding
[UNKNOWN]
sphinganine kinase activity [UNKNOWN] DNA binding [UNKNOWN] ATP binding [UNKNOWN] calmodulin binding [UNKNOWN] protein binding [UNKNOWN][IPI] D-erythro-sphingosine kinase activity [UNKNOWN][IDA] diacylglycerol kinase activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MQPADCPRGL LPRPCRVLVL LNPRGGKGKA LKLFQSRVRP LLEEAEVSFK LMLTERQNHA 60 61 RELVCAEELG HWDALAVMSG DGLMHEVVNG LMERPDWESA IQKPLCSLPG GSGNALAASL 120 121 NYYAGHEQVT NEDLLINCTL LLCCRQLSPM NLLSLHTASG RQLYSVLSLS WGFVADVDLE 180 181 SEKYRSLGEI RFTVGTFFRL ASLRIYQGQL AYLPVGKAAS KIPASSLAQK GPANTYLVPL 240 241 EEPVPPHWTV VPEQDFVLVL VLLHTHLSTE MFAAPMGRCE AGVMHLFYIR AGVSRAMLVR 300 301 LFLAMQKGKH MDLDCPYLVH VPVVAFRLEP RNQRGVFSVD GELMVCEAVQ GQVHPNYLWM 360 361 VSGSSDSPSG RDSQRRPPPE EPI |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.92 |
Source: Reynolds et al. (2008)