Protein Overview: HDAC4_MOUSE

General Information:
Name(s) found:	HDAC4_MOUSE [Swiss-Prot]
Description(s) found: Found 16 descriptions. SHOW ALL	Histone deacetylase 4 OS=Mus musculus GN=Hdac4 PE=1 SV=1 [Swiss-Prot]
Organism:	Mus musculus
Length:	1076 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IMP] Z disc [UNKNOWN] cytoplasm [UNKNOWN][IMP] histone deacetylase complex [IEA] cytosol [IDA] neuromuscular junction [IDA] A band [UNKNOWN] actomyosin [IDA] sarcomere [UNKNOWN]
Biological Process:	chromatin modification [IEA] response to denervation involved in regulation of muscle adaptation [IMP] transcription [IEA] negative regulation of cell proliferation [IDA][IMP] negative regulation of glycolysis [IMP] osteoblast development [IMP] regulation of transcription [IEA] negative regulation of osteoblast differentiation [IMP] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA][IGI] skeletal system development [IMP] negative regulation of transcription, DNA-dependent [IDA][IMP] regulation of skeletal muscle fiber development [IGI] response to drug [UNKNOWN] regulation of striated muscle cell differentiation [IGI] positive regulation of gene-specific transcription from RNA polymerase II promoter [IMP] regulation of cardiac muscle contraction by calcium ion signaling [IMP]
Molecular Function:	DNA binding [IDA] protein binding [IPI] histone deacetylase activity [UNKNOWN] transcription corepressor activity [IGI] transcription activator activity [IMP] transcription repressor activity [IDA][IMP] protein deacetylase activity [IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPTAVPMD LRLDHQFSLP  60
   61 LEPALREQQL QQELLALKQK QQIQRQILIA EFQRQHEQLS RQHEAQLHEH IKQQQEMLAM 120
  121 KHQQELLEHQ RKLERHRQEQ ELEKQHREQK LQQLKNKEKG KESAVASTEV KMKLQEFVLN 180
  181 KKKALAHRNL NHCISSDPRY WYGKTQHSSL DQSSPPQSGV SASYNHPVLG MYDAKDDFPL 240
  241 RKTASEPNLK LRSRLKQKVA ERRSSPLLRR KDGPVATALK KRPLDVTDSA CSSAPGSGPS 300
  301 SPNSSSGNVS TENGIAPTVP SAPAETSLAH RLVTREGSVA PLPLYTSPSL PNITLGLPAT 360
  361 GPAAGAAGQQ DAERLALPAL QQRILFPGTH LTPYLSTSPL ERDGAAAHNP LLQHMVLLEQ 420
  421 PPTQTPLVTG LGALPLHSQS LVGADRVSPS IHKLRQHRPL GRTQSAPLPQ NAQALQHLVI 480
  481 QQQHQQFLEK HKQQFQQQQL HLSKIISKPS EPPRQPESHP EETEEELREH QALLDEPYLD 540
  541 RLPGQKEPSL AGVQVKQEPI ESEEEEAEAT RETEPGQRPA TEQELLFRQQ ALLLEQQRIH 600
  601 QLRNYQASME AAGIPVSFGS HRPLSRAQSS PASATFPMSV QEPPTKPRFT TGLVYDTLML 660
  661 KHQCTCGNTN SHPEHAGRIQ SIWSRLQETG LRGKCECIRG RKATLEELQT VHSEAHTLLY 720
  721 GTNPLNRQKL DSSLTSVFVR LPCGGVGVDS DTIWNEVHSS GAARLAVGCV VELVFKVATG 780
  781 ELKNGFAVVR PPGHHAEEST PMGFCYFNSV AVAAKLLQQR LNVSKILIVD WDVHHGNGTQ 840
  841 QAFYNDPNVL YMSLHRYDDG NFFPGSGAPD EVGTGPGVGF NVNMAFTGGL EPPMGDAEYL 900
  901 AAFRTVVMPI ANEFAPDVVL VSSGFDAVEG HPTPLGGYNL SAKCFGYLTK QLMGLAGGRL 960
  961 VLALEGGHDL TAICDASEAC VSALLGNELE PLPEKVLHQR PNANAVHSME KVMDIHSKYW1020
 1021 RCLQRLSSTV GHSLIEAQKC EKEEAETVTA MASLSVGVKP AEKRSEEEPM EEEPPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HDAC4_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: