Protein Overview: CG8850-PB

General Information:
Name(s) found:	CG8850-PB / FBpp0087080 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45551088\|ref\|NP_725122.2\| CG8850, isoform B [Drosophila melanogaster] [NCBI NR] gi\|45445572\|gb\|AAF58538.3\| CG8850, isoform B [Drosophila melanogaster] [NCBI NR] gi\|226693435\|gb\|ACO72865.1\| LP02553p [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG8850 (CG8850, FBgn0033708). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8186283..8189741. It has the cytological map location 48F6. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity; potassium:amino acid symporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: neurotransmitter transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (AAF58538) CG8850-PB [DrosMelano7227.FASTAC.txt] CG8850-PB, isoform B [Drosophila melanogaster]gi\|45551088\|ref\|NP_725122.2\| CG8850-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:complement(8186437..8186580,8186643..8187381,8187438..8187815,8187880..8188099,8188159..8188441,8188503..8188628); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBas [fly-100309-contam.fasta] CG8850-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:complement(8186437..8186580,8186643..8187381,8187438..8187815,8187880..8188099,8188159..8188441,8188503..8188628); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:complement(8186437..8186580,8186643..8187381,8187438..8187815,8187880..8188099,8188159..8188441,8188503..8188628); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Transporter OS=Drosophila melanogaster GN=CG8850-RB PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:complement(8186437..8186580,8186643..8187381,8187438..8187815,8187880..8188099,8188159..8188441,8188503..8188628); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538,FlyMine:FBpp0087080,modMine:FBpp0087080; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:complement(join(12300998..12301123,12300654..12300936,12300375..12300594,12299933..12300310,12299138..12299876,12298932..12299075)); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538,FlyMine:FBpp0087080,modMine:FBpp0087080; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:complement(join(12300998..12301123,12300654..12300936,12300375..12300594,12299933..12300310,12299138..12299876,12298932..12299075)); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538,FlyMine:FBpp0087080,modMine:FBpp0087080; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0087080 type=protein; loc=2R:complement(join(12300998..12301123,12300654..12300936,12300375..12300594,12299933..12300310,12299138..12299876,12298932..12299075)); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538,FlyMine:FBpp0087080,modMine:FBpp0087080; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:complement(join(12300998..12301123,12300654..12300936,12300375..12300594,12299933..12300310,12299138..12299876,12298932..12299075)); ID=FBpp0087080; name=CG8850-PB; parent=FBgn0033708,FBtr0087972; dbxref=GB_protein:AAF58538.2,FlyBase:FBpp0087080,FlyBase_Annotation_IDs:CG8850-PB,GB_protein:AAF58538.3,REFSEQ:NP_725122,GB_protein:AAF58538,UniProt/TrEMBL:A1Z8V9,FlyMine:FBpp0087080,modMine:FBpp0087080; MD5=4998be6d2d2f5dac73161b25c3d05620; length=629; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	629 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA]
Biological Process:	neurotransmitter transport [ISS]
Molecular Function:	neurotransmitter transporter activity [ISS] neurotransmitter:sodium symporter activity [IEA] potassium:amino acid symporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDDAEYQKL RRNMQGAQGS REGHPGSNDG ISTVIYSAEG EELTINCEAE SESSGQRDQW  60
   61 SRGVEFLFSC IALSVGLGNV WRFPFIALEN GGGAFLIPYV IVLLLIGRPV YYLEVIIGQF 120
  121 SSRGCIRAFD MAPIMRGIAY GQVYSTALAT TYYACIMALT IRYLVASFSE VLPWTYCLVE 180
  181 WGKSCVATGA TAANDSSIVQ GVSSAELFFT QTVLREPESL DDNGLGTPSW DLVLCLLATW 240
  241 VIIGTILSKG IRSSGKASYF LALFPYVIMI VLLIRAVTLP GAWQGIVYFL KPQWSQLLNP 300
  301 HVWYAAITQM FFSLAICFGT LVMYASFNDF NKNVHKDVII ITTIDSLTSI LAGCIIFGIL 360
  361 GNLAFETNTK DISQVVKGGA GLAFISYPEA IAKFKYLPQL FAVLFFFMLL VLGIGSNIGM 420
  421 ASAVVNVVKD RFTHLPHWLL AVSASIIGFL CGLVYMTPGG QFVLNLVDFY GCTFIALVLA 480
  481 IAELLAVGWI YGVKRICSDI EFMLNVKTSF YWRICWAIVA PGLMFLVLVY MLFSYEPLTY 540
  541 RGVQYPPVYY MAGWIIWGLG VLQLPFWALV TIYQQPGKTF GSKFGLAMQP TANWGPLQTQ 600
  601 KFEAYIIHRK READFKSPRG GYLFDNIFG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..537]	PSI-BLAST	54.0	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
2	View Details	[538..629]	deduced	N/A	No confident structure predictions are available.

Protein Overview: CG8850-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: