Protein Overview: ABCB7-PA

General Information:
Name(s) found:	ABCB7-PA / FBpp0072637 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45551501\|ref\|NP_728642.2\| CG7955, isoform A [Drosophila melanogaster] [NCBI NR] gi\|45445737\|gb\|AAF47525.2\| CG7955, isoform A [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\ABCB7 (CG7955, FBgn0035244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1618392..1623413. It has the cytological map location 62A8-62A9. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled to transmembrane movement of substances; transporter activity; heme transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: heme transport; iron-sulfur cluster assembly. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] (AAF47525) CG7955-PA [DrosMelano7227.FASTAC.txt] CG7955-PA, isoform A [Drosophila melanogaster]gi\|45551501\|ref\|NP_728642.2\| CG7955-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=CG7955-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FB [fly-100309-contam.fasta] CG7955-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=CG7955-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] ABCB7, isoform A OS=Drosophila melanogaster GN=ABCB7 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525,FlyMine:FBpp0072637,modMine:FBpp0072637; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] ABCB7, isoform A OS=Drosophila melanogaster GN=ABCB7 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525,FlyMine:FBpp0072637,modMine:FBpp0072637; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525,FlyMine:FBpp0072637,modMine:FBpp0072637; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0072637 type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525,FlyMine:FBpp0072637,modMine:FBpp0072637; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(1618501..1618617,1620428..1620554,1620817..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072637; name=ABCB7-PA; parent=FBgn0035244,FBtr0072754; dbxref=GB_protein:AAF47525.1,GB_protein:AAF47525.2,FlyBase:FBpp0072637,FlyBase_Annotation_IDs:CG7955-PA,REFSEQ:NP_728642,GB_protein:AAF47525,UniProt/TrEMBL:Q9W0C5,FlyMine:FBpp0072637,modMine:FBpp0072637; MD5=1faa8b61f6f15458b8f6e1a8ce9628bd; length=743; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	743 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] ATP-binding cassette (ABC) transporter complex [ISS] mitochondrial inner membrane [ISS]
Biological Process:	transmembrane transport [IEA] heme transport [ISS] iron-sulfur cluster assembly [ISS]
Molecular Function:	ATP binding [IEA] ATPase activity, coupled to transmembrane movement of substances [ISS] heme transporter activity [ISS] transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGLLHLTKQ CSIHLPAHLG RAKCYTLAKG PGTHVQARVL YSSLTKVDDK NSSDAKRKKI  60
   61 TPFTPTPGSK LLGGVFGKKA KGGAPAAAAA KTTTLQRQRP YRPQQQQSRL CHVHIGGGSD 120
  121 GGSGLGKLDA PEVTSKDMLR AMMAYIWPKE DPLVRKRVGI SLGLLAGSKL LTVCVPFLFK 180
  181 GAVDTMTTLN MDTAPDAVLS AATALMLGYG IARASAAGFN ELRNAVFAKV AHHSIRKIAS 240
  241 NVFLHLHNLD LAFHLNKQTG ALSKTIDRGS RGINFVLSAM VFNIVPTIFE LALVSSILGV 300
  301 KCGLAFAGVS MGCVGIYAAY TLSVTQWRTQ FRVFMNQAEN EAGNKAVDSL INYETVKYFN 360
  361 NEKYEAGCYN EVLKKYEAAS LKTSSSLALL NFGQNAIFSS ALSLIMVLAA KEIAQGNMTV 420
  421 GDLVMVNALL FQLSIPLGFL GSVYREVRQA LLDMRAMFTL MNVDSSIQTA ANAQPLFVDT 480
  481 TNSSIEFRNV SFEYEPGKPI FRDLSFTIPA GKNVAIVGGS GSGKSSMVRL LFRFFEPNSG 540
  541 KVLIGGQDIS AVDLESLRKV IAVVPQDSVL FHNTIEHNIH YGNLSKSHAE VQNAARMADL 600
  601 HDSIMSWPGQ YSTQVGERGL KLSGGEKQRV AIARAILKNT PILIFDEATS SLDSITEHNI 660
  661 LQALTRATSG RTSICIAHRL STVKDADEIL VLENGRVGER GTHSELLRQN GLYARLWETQ 720
  721 TQQFDPSREI NEEVAAKKTR GVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ABCB7-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: