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Protein Overview: TRMA_ECOLI

General Information:
Name(s) found: TRMA_ECOLI [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • tRNA (uracil-5-)-methyltransferase (EC 2.1.1.35) (tRNA(M-5-U54)-methyltransferase) (RUMT) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 366 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPEHLPTEQ YEAQLAEKVV RLQSMMAPFS DLVPEVFRSP VSHYRMRAEF RIWHDGDDLY  60
   61 HIIFDQQTKS RIRVDSFPAA SELINQLMTA MIAGVRNNPV LRHKLFQIDY LTTLSNQAVV 120
  121 SLLYHKKLDD EWRQEAEALR DALRAQNLNV HLIGRATKTK IELDQDYIDE RLPVAGKEMI 180
  181 YRQVENSFTQ PNAAMNIQML EWALDVTKGS KGDLLELYCG NGNFSLALAR NFDRVLATEI 240
  241 AKPSVAAAQY NIAANHIDNV QIIRMAAEEF TQAMNGVREF NRLQGIDLKS YQCETIFVDP 300
  301 PRSGLDSETE KMVQAYPRIL YISCNPETLC KNLETLSQTH KVERLALFDQ FPYTHHMECG 360
  361 VLLTAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..366] PSI-BLAST 63.39794 Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  4.64500705012502 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.60300178039953 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.57389022626587 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.74830027382001 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.6174490060285 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.00112136063228 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  2.74535979387581 bayes_pls_golite062009
  • transferase activity
    		•  2.42370637689376 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.15176183511624 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  2.03602074114015 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.93015827477588 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  1.8182614465692 bayes_pls_golite062009
  • catalytic activity
    		•  1.62377578202456 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.42140847541194 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  1.40233857644962 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  1.40233857644962 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  1.26573118969035 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.88654745691593 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  0.67380437956274 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  0.661941246551751 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  0.661941246551751 bayes_pls_golite062009
  • O-methyltransferase activity
    		•  0.59365370184158 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  0.51194141894759 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  0.51194141894759 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  0.355464145533041 bayes_pls_golite062009
  • tRNA (guanine) methyltransferase activity
    		•  0.355378060639199 bayes_pls_golite062009
  • rRNA (cytosine) methyltransferase activity
    		•  0.346042596102079 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle