Protein Overview: unc-10

General Information:
Name(s) found:	unc-10 / CE30169 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006750 locus:unc-10 Rab-3-interacting molecule unc-10 status:Confirmed UniProt:Q22366 protein_id:CCD71364.1 [WormBase] gi\|41017531\|sp\|Q22366.2\|RIM_CAEEL RecName: Full=Rab-3-interacting molecule unc-10; Short=Rim; AltName: Full=Uncoordinated protein 10 [NCBI NR] gi\|25150782\|ref\|NP_741831.1\| UNCoordinated family member (unc-10) [Caenorhabditis elegans] [NCBI NR] gi\|18652614\|gb\|AAB37028.2\| Uncoordinated protein 10, isoform a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|13925301\|gb\|AAK49331.1\|AF257062_1 Rab3-interacting molecule UNC-10 [Caenorhabditis elegans] [NCBI NR] Rab-3-interacting molecule unc-10 OS=Caenorhabditis elegans GN=unc-10 PE=1 SV=2 [Swiss-Prot] [wormpep79.fasta] CE30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed SW:Q22366 protein_id:AAB37028.2 [wormpep150.fasta] 30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed SW:Q22366 protein_id:AAB37028.2 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-10, Rab-3 Interacting Molecule (175.5 kD) (unc-10) [Caenorhabditis elegans]gi\|18652614\|gb\|AAB37028.2\| Uncoordinated protein 10, isoform a [Caenorhabditis elegans]gi\|13925301\|gb\|AAK49331.1\| Rab3-interacting molecule UNC-10 [C [nrdb_11152004_Chlamydomonas] locus:unc-10 C2 domain of protein kinase C status:Confirmed TR:Q22366 protein_id:AAB37028.2 [wormpep115.fasta.reversed] CE30169 locus:unc-10 C2 domain of protein kinase C status:Confirmed [wormpep80.hongbin] CE30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed UniProt:RIM_CAEEL protein_id:AAB37028.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed UniProt:RIM_CAEEL protein_id:AAB37028.2\| [wormORF-contam.fasta] Uncoordinated protein 10, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta] Rab-3-interacting molecule unc-10 (Rim) (Uncoordinated protein 10) [nr-271106-contam.fasta] Rab3-interacting molecule UNC-10 [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-10) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed UniProt:Q22366 protein_id:AAB37028.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE30169 WBGene00006750 locus:unc-10 C2 domain of protein kinase C status:Confirmed UniProt:Q22366 protein_id:CCD71364.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE30169 WBGene00006750 locus:unc-10 status:Confirmed UniProt:Q22366 protein_id:CCD71364.1 Rab-3-interacting molecule unc-10 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1563 amino acids
Gene Ontology:
Cellular Component:	presynaptic active zone [IDA] axon [IDA]
Biological Process:	mating behavior [IMP] regulation of pharyngeal pumping [IMP] locomotory behavior [IMP] synaptic vesicle priming [IDA] locomotion [IMP] positive regulation of synaptic transmission [IDA] protein localization [IMP] positive regulation of synaptic transmission, cholinergic [IMP] intracellular protein transport [IEA] defecation [IMP] positive regulation of multicellular organism growth [IMP]
Molecular Function:	zinc ion binding [IEA] protein binding [IEA][IPI] protein C-terminus binding [IPI] calcium ion binding [ISS] Rab GTPase binding [IEA][IGI] GTP-dependent protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDPSMMPDL SHLSAEEREI IENVFKRQKD EEAKETQISQ KASEELSELD KQITERKETS  60
   61 KKLVGTQDDA ICQICQKTKF ADGIGHKCFY CQLRSCARCG GRAQSKNKAI WACSLCQKRQ 120
  121 QILAKTGKWF QPEEQPQPKI SGSEPSPSPQ PLTDDNVPEP QQRRAEPPDK MNTPNYQNNQ 180
  181 QPRGMGMQPN HNQTQQNFMN QNQNSNQHPN QNHNQNQMQN PHQNQNHVQN NHQGANNHQQ 240
  241 NNRRAMQQQP MSQNQANQIN QMNQNQNQQQ SHNQNMTQNQ RNQTGPQNQQ RTNDSRTMKQ 300
  301 TPQQQPSQYQ NNVGAAHQHH NQHGQQEQHH QQMNEQRTDN NRMRENTNGQ GGMFNRQPSL 360
  361 EQTTPMNKYN HVEDDGMNQR PTFYTGNSEN DQRQFDGQMQ QGSQQNNQNQ NQNNRNLRKN 420
  421 TVSRVTEEDY ASSSNFESKK QRNNSSQSQS NTQGVRACPS TDDHLNRVKN RLHRQLRSMS 480
  481 SSEEDIIAGG GGNTLKMSTS AVVASGGKTA FHDDMGASNV QRLSEECNSE KDLLRYIYGD 540
  541 HKNSDSSSLG AGVGGSGGGG VLSGNSVLKS KSHALLKGSY QGGLDMQANR RRDKSLSLSP 600
  601 SRNDHFGTGS ISGGDLLASR IRTFLSHPVT WQPSADQKKL IGHMILHRTE NSAANGDLGL 660
  661 KIVGGRRTDT GKLGAFITQV KPGSVADTIG RLRPGDEVVE WNGQSLQNAT YEQVYDSIAA 720
  721 SRYDTSVELI VSRSAIIPGG DDFLNLTPSQ MSSSAYSRVP SAYPSQFQRQ LPNPDLFLDI 780
  781 HPALQQLSLP HSQSAVFPHN NTLTSRNRST SSYYYSDVPD LGVPSNREMQ ESQAFGTGHI 840
  841 FGRIEVSFVY SHHDRQLSVA LVRGFDLPPR SDGTPRNPYV KIFLLPDRSE KSRRQSAVIA 900
  901 ETLMPVWDEV FYYNGLTEPM LLQRVLELTV WDYDKFGTNS FLGETLIDLA SVPLDGEHSL 960
  961 MCILVDMDDD NPLRTVISIF KFHVIILTFL QRLKLRKASY NAPTRRPQSE LNYYDHSSNY1020
 1021 YDHISQNIDK QPHHHHLAPN DEENDEYIDD DELENDIDLA TGGGARKSRT YRREKGMHGG1080
 1081 HGYADWTQNH QRQSGYTSDH GYGRQNMIGR AYNRRQQRRP RSATALSQME REDMYDPTRK1140
 1141 HRDDNEYSMR ESVRHGSQYY LGDQPLYEDG RYKISQGQMT PKQHNQQHQP HPLSQAHQQQ1200
 1201 QTAGVQPQHH QGFQQQQHPQ QPNQQMQQMQ PPMPNQGYYS DGSETLSVHS TNSMPTTMTT1260
 1261 VNRRNMNANN TSNDNTSFAE TPTANTNRVP IKETKQNSLA SSSSVAGGGS AANNVMKERK1320
 1321 KSLMTRFIPG RGAEGKRTGF ARSEEVGIPG NLSSDRLTEP TPPFLKQASK ESTDSAHSDK1380
 1381 FARQCWLPVL ADGPLGTFVD NLGPGQVVGR QVLASPVLGE IQIALMAGRS GIDVEIIKAK1440
 1441 NLVVKPGVKV CPAPYVKVYL MEGKQCIAKA KTNAATKTTS PLFQQHLIFN DSPKKKTLQV1500
 1501 TVLGDYGRME RKVFMGISQI RLEDLELGSQ PLIGWYKLFH SSSLAGTGPV RKDSDVSVGG1560
 1561 AQQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-10

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: