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Protein Overview: pri-2

General Information:
Name(s) found: pri-2 / CE24028 [WormBase]
Description(s) found:
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  • WBGene00004181 locus:pri-2 DNA primase large subunit status:Confirmed UniProt:O02334 protein_id:CAB03469.2 [WormBase]
  • pir||T26114 hypothetical protein W02D9.1 - Caenorhabditis elegans [NCBI NR]
  • gi|5824647|emb|CAB03469.2| C. elegans protein W02D9.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17508509|ref|NP_493176.1| DNA PRImase homolog family member (pri-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|14917028|sp|O02334.2|PRI2_CAEEL RecName: Full=DNA primase large subunit [NCBI NR]
  • DNA primase large subunit OS=Caenorhabditis elegans GN=pri-2 PE=3 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Partially_confirmed SW:O02334 protein_id:CAB03469.2 [wormpep150.fasta]
  • 24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Partially_confirmed SW:O02334 protein_id:CAB03469.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • DNA PRImase homolog (58.3 kD) (pri-2) [Caenorhabditis elegans]gi|5824647|emb|CAB03469.2| Hypothetical protein W02D9.1 [Caenorhabditis elegans]gi|7508838|pir||T26114 hypothetical protein W02D9.1 - Caenorhabditis elegansgi|14917028|sp|O02334|PRI2_CAEEL P [nrdb_11152004_Chlamydomonas]
  • locus:pri-2 DNA primase 58 KD subunit status:Partially_confirmed SW:O02334 protein_id:CAB03469.2 [wormpep115.fasta.reversed]
  • CE24028 locus:pri-2 DNA primase 58 KD subunit status:Partially_confirmed SW:O02334 protein_id:CAB03469.2 [wormpep80.hongbin]
  • CE24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Confirmed UniProt:PRI2_CAEEL protein_id:CAB03469.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Confirmed UniProt:PRI2_CAEEL protein_id:CAB03469.2| [wormORF-contam.fasta]
  • Hypothetical protein W02D9.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • DNA PRImase homolog family member (pri-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • DNA primase large subunit [nr-271106-contam.fasta]
  • CE24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Confirmed SW:O02334 protein_id:CAB03469.2 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE24028 WBGene00004181 locus:pri-2 DNA primase 58 KD subunit status:Confirmed UniProt:O02334 protein_id:CAB03469.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24028 WBGene00004181 locus:pri-2 status:Confirmed UniProt:O02334 protein_id:CAB03469.2 DNA primase large subunit [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 503 amino acids

    Gene Ontology:
    Cellular Component: alpha DNA polymerase:primase complex [IEALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    nucleus organization [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    DNA replication, synthesis of RNA primer [IEALink to PubMed article]
    Molecular Function: DNA primase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFTSGANKL NDNRNVRTKI SSNRQSIKTA PTKAAEIPEY LQLYQTPPGD DISLTEFDDI  60
   61 AMERLKLLKS FENLKDSVSL YNDEFKDKFR KLCDGTKLIV FPDQKPPHQE EVYELWRRDN 120
  121 IGHFILRLAF CRTPENQKWL TQIEGDFLRF RLRQEREQVL DSALANVNFT IEKLGYTEKQ 180
  181 AMIEDLEAAC QFNLFEAPNK TFYKVDFIDA IELIRRGSVH LKKGFAYFPF DDLVTILVTK 240
  241 MKNNMMAAMA RSFKHLAILE EEGRLLPRLS LLSNNAYSGK DYNGEQPDGS IIVTRHMIDK 300
  301 LSRRSFAPCM KQMHNHLRVN HHLKYGARRQ YGLFLKGIGL SLDEAIAMMR DEFTKKITSD 360
  361 KFDKEYGYNI RYMYGKEGRR VAQTAMSCAT IILRNPPSAV DCHGCPFRHS EKQVLKQKLG 420
  421 SDAILKKEQI ERIAELAELN QYDKACTRYF EFMHNLEEGG LGQLITHPNQ FYEESQKIVA 480
  481 ERIAAKQESQ EAPAPKIEKM DTE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] MSA 1.066985 View MSA. No confident structure predictions are available.
    2 View Details [108..305] PSI-BLAST 14.69897 No description for 2dlaA was found.
    3 View Details [306..406] MSA 2.071977 View MSA. No confident structure predictions are available.
    4 View Details [407..503] MSA 1.040991 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle