Protein Overview: pgp-1

General Information:
Name(s) found:	pgp-1 / CE11932 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00003995 locus:pgp-1 Multidrug resistance protein pgp-1 status:Partially_confirmed UniProt:P34712 protein_id:CAB01232.1 [WormBase] gi\|7505559\|pir\|\|T23476 hypothetical protein K08E7.9 - Caenorhabditis elegans [NCBI NR] gi\|3878418\|emb\|CAB01232.1\| C. elegans protein K08E7.9, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|29429182\|sp\|P34712.2\|MDR1_CAEEL RecName: Full=Multidrug resistance protein 1; AltName: Full=P-glycoprotein A [NCBI NR] gi\|17541710\|ref\|NP_502413.1\| P-GlycoProtein related family member (pgp-1) [Caenorhabditis elegans] [NCBI NR] Multidrug resistance protein pgp-1 OS=Caenorhabditis elegans GN=pgp-1 PE=1 SV=2 [Swiss-Prot] Multidrug resistance protein 1 OS=Caenorhabditis elegans GN=pgp-1 PE=2 SV=2 [Swiss-Prot] [wormpep67.fasta] CE11932 WBGene00003995 locus:pgp-1 multidrug resistance protein status:Partially_confirmed SW:P34712 protein_id:CAB01232.1 [wormpep150.fasta] 11932 WBGene00003995 locus:pgp-1 multidrug resistance protein status:Partially_confirmed SW:P34712 protein_id:CAB01232.1 [wormpep130-phg-ecoli-orf-rand.fasta] P-GlycoProtein related (pgp-1) [Caenorhabditis elegans]gi\|3878418\|emb\|CAB01232.1\| Hypothetical protein K08E7.9 [Caenorhabditis elegans]gi\|7505559\|pir\|\|T23476 hypothetical protein K08E7.9 - Caenorhabditis elegansgi\|29429182\|sp\|P34712\|MDR1_CAEEL Multidru [nrdb_11152004_Chlamydomonas] locus:pgp-1 multidrug resistance protein status:Partially_confirmed SW:P34712 protein_id:CAB01232.1 [wormpep115.fasta.reversed] CE11932 locus:pgp-1 multidrug resistance protein status:Partially_confirmed TR:Q21349 protein_id:CAB01232.1 [wormpep80.hongbin] CE11932 WBGene00003995 locus:pgp-1 multidrug resistance protein status:Partially_confirmed UniProt:P34712 protein_id:CAB01232.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE11932 WBGene00003995 locus:pgp-1 multidrug resistance protein status:Partially_confirmed UniProt:P34712 protein_id:CAB01232.1\| [wormORF-contam.fasta] P-GlycoProtein related family member (pgp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Multidrug resistance protein 1 (P-glycoprotein A) [nr-271106-contam.fasta] hypothetical protein K08E7.9 - Caenorhabditis elegans [nr-271106-contam.fasta] Hypothetical protein K08E7.9 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE11932 WBGene00003995 locus:pgp-1 status:Partially_confirmed UniProt:P34712 protein_id:CAB01232.1 Multidrug resistance protein pgp-1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1321 amino acids
Gene Ontology:
Cellular Component:	Gram-negative-bacterium-type cell wall [IEA] membrane [IEA] integral to membrane [IEA] outer membrane-bounded periplasmic space [IEA]
Biological Process:	protein transport [IEA] transport [IEA] amino acid transport [IEA] nodulation [IEA] cell division [IEA] cobalt ion transport [IEA] lipid transport [IEA] D-methionine transport [IEA] phosphate transport [IEA] nitrate transport [IEA] phosphonate transport [IEA] polyamine transport [IEA] cytochrome complex assembly [IEA] peptide transport [IEA] molybdate ion transport [IEA]
Molecular Function:	ATPase activity [IEA] phosphate transmembrane transporter activity [IEA] ATPase activity, coupled to transmembrane movement of substances [IEA] nitrate transmembrane transporter activity [IEA] peptide transporter activity [IEA] molybdate ion transmembrane transporter activity [IEA] protein transporter activity [IEA] amino acid transmembrane transporter activity [IEA] cysteine-type peptidase activity [IEA] transporter activity [IEA] nucleotide binding [IEA] D-methionine transmembrane transporter activity [IEA] ATP binding [IEA] inorganic phosphate transmembrane transporter activity [IEA] nucleoside-triphosphatase activity [IEA] polyamine-transporting ATPase activity [IEA] phosphonate transmembrane-transporting ATPase activity [IEA] toxin transporter activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNGSLRQS LRTLDSFSLA PEDVLKTAIK TVEDYEGDNI DSNGEIKITR DAKEEVVNKV  60
   61 SIPQLYRYTT TLEKLLLFIG TLVAVITGAG LPLMSILQGK VSQAFINEQI VINNNGSTFL 120
  121 PTGQNYTKTD FEHDVMNVVW SYAAMTVGMW AAGQITVTCY LYVAEQMNNR LRREFVKSIL 180
  181 RQEISWFDTN HSGTLATKLF DNLERVKEGT GDKIGMAFQY LSQFITGFIV AFTHSWQLTL 240
  241 VMLAVTPIQA LCGFAIAKSM STFAIRETLR YAKAGKVVEE TISSIRTVVS LNGLRYELER 300
  301 YSTAVEEAKK AGVLKGLFLG ISFGAMQASN FISFALAFYI GVGWVHDGSL NFGDMLTTFS 360
  361 SVMMGSMALG LAGPQLAVLG TAQGAASGIY EVLDRKPVID SSSKAGRKDM KIKGDITVEN 420
  421 VHFTYPSRPD VPILRGMNLR VNAGQTVALV GSSGCGKSTI ISLLLRYYDV LKGKITIDGV 480
  481 DVRDINLEFL RKNVAVVSQE PALFNCTIEE NISLGKEGIT REEMVAACKM ANAEKFIKTL 540
  541 PNGYNTLVGD RGTQLSGGQK QRIAIARALV RNPKILLLDE ATSALDAESE GIVQQALDKA 600
  601 AKGRTTIIIA HRLSTIRNAD LIISCKNGQV VEVGDHRALM AQQGLYYDLV TAQTFTDAVD 660
  661 SAAEGKFSRE NSVARQTSEH EGLSRQASEM DDIMNRVRSS TIGSITNGPV IDEKEERIGK 720
  721 DALSRLKQEL EENNAQKTNL FEILYHARPH ALSLFIGMST ATIGGFIYPT YSVFFTSFMN 780
  781 VFAGNPADFL SQGHFWALMF LVLAAAQGIC SFLMTFFMGI ASESLTRDLR NKLFRNVLSQ 840
  841 HIGFFDSPQN ASGKISTRLA TDVPNLRTAI DFRFSTVITT LVSMVAGIGL AFFYGWQMAL 900
  901 LIIAILPIVA FGQYLRGRRF TGKNVKSASE FADSGKIAIE AIENVRTVQA LAREDTFYEN 960
  961 FCEKLDIPHK EAIKEAFIQG LSYGCASSVL YLLNTCAYRM GLALIITDPP TMQPMRVLRV1020
 1021 MYAITISTST LGFATSYFPE YAKATFAGGI IFGMLRKISK IDSLSLAGEK KKLYGKVIFK1080
 1081 NVRFAYPERP EIEILKGLSF SVEPGQTLAL VGPSGCGKST VVALLERFYD TLGGEIFIDG1140
 1141 SEIKTLNPEH TRSQIAIVSQ EPTLFDCSIA ENIIYGLDPS SVTMAQVEEA ARLANIHNFI1200
 1201 AELPEGFETR VGDRGTQLSG GQKQRIAIAR ALVRNPKILL LDEATSALDT ESEKVVQEAL1260
 1261 DRAREGRTCI VIAHRLNTVM NADCIAVVSN GTIIEKGTHT QLMSEKGAYY KLTQKQMTEK1320
 1321 K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: pgp-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: