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Protein Overview: lsk1

General Information:
Name(s) found: lsk1 / SPAC2F3.15 [Sanger Pombe]
Description(s) found:
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  • pir||T38547 probable cell division protein kinase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74675947|sp|O14098.1|CTK1_SCHPO RecName: Full=CTD kinase subunit alpha; Short=CTDK-I subunit alpha; AltName: Full=CTD kinase subunit 1; AltName: Full=Latrunculin sensitive kinase 1 [NCBI NR]
  • gi|2408067|emb|CAB16269.1| P-TEFb-associated cyclin-dependent protein kinase Lsk1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115305|ref|NP_594393.1| latrunculin sensitive kinase Lsk1 (PMID 15537703) [Schizosaccharomyces pombe] [NCBI NR]
  • latrunculin sensitive kinase Lsk1 [Sanger Pombe]
  • CTD kinase subunit alpha OS=Schizosaccharomyces pombe GN=lsk1 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE CELL DIVISION PROTEIN KINASE: O14098; [pompepVF.fasta]
  • Putative serine/threonine protein kinase [pompep4896]
  • |||putative serine/threonine protein kinase [pompepnew.fasta]
  • SPAC2F3.15 protein [4896.FASTAC]
  • |||serine/threonine protein kinase (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative cell division protein kinase [Schizosaccharomyces pombe]gi|2408067|emb|CAB16269.1| SPAC2F3.15 [Schizosaccharomyces pombe]gi|7492454|pir||T38547 probable cell division protein kinase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O14098) Putative serine/threonine protein kinase [pompep4896_normal_reversed]
  • |lsk1||P-TEFb-associated cyclin-dependent protein kinase Lsk1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC2F3.15 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC2F3.15 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |lsk1||latrunculin sensitive kinase Lsk1|Schizosaccharomyces pombe|chr 1|||Manual [spombe-190209-contam.fasta]
  • CTD kinase subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lsk1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 593 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    positive transcription elongation factor complex b [NAS]
    nucleolus [IDALink to PubMed article]
    Biological Process: phosphorylation of RNA polymerase II C-terminal domain [IMPLink to PubMed article]
    positive regulation of septation initiation signaling [IGILink to PubMed article]
    contractile ring maintenance involved in cell cycle cytokinesis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    RNA polymerase II carboxy-terminal domain kinase activity [IDALink to PubMed article]
    cyclin-dependent protein kinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYSKSTIYR RQGTEPNSHF RRTVEEKSQL SGTNEESLGG HTLSSNAFKN NSSSISPSSS  60
   61 AKDPREQRKR TFPLNDTHSS RARQHERPFR SRKSRRRKGK KAFSPRPGSP PSPSFYRSGS 120
  121 QKRARNLTTK DYFAKRSESS SSASVSPISP SANRNDSKRQ ASSFRRSPPS SVHMKPSAFN 180
  181 GRKVSRRPSS SPPPIPSIPH ETTSSDTQKK SSVSSGFPEN KHGKFHFHIP NERRSRFDQP 240
  241 PSKRMALTST ARESVPAPLP SPPSGPIYTY TYPKPAYEKI DQIGEGTYGK VYKAINTVTG 300
  301 DLVALKRIRL EQEKDGFPIT TVREVKILQR LRHKNIVRLL EIMVEKSSVY MVFEYMDHDL 360
  361 TGVLLNSQLH FTPGNIKHLS KQIFEALAYL HHRGVLHRDI KGSNILLNNN GDLKFADFGL 420
  421 ARFNTSSKSA NYTNRVITLW FRPPELLLGE TAYDTAVDIW SAGCIVMELF TGKPFFQGRD 480
  481 EISQLEVIYD MMGTPDVHSW PEVKNLPWYE LLKPVEEKKS RFVETFKEIL SPAAIDLCQK 540
  541 LLALNPFCRP SAHETLMHEY FTSESPPPEP AVILKNMQGS WHEWESKKRK SKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..193] deduced N/A No confident structure predictions are available.
    2 View Details [194..528] PSI-BLAST 41.0 No description for 2ozoA was found.
    3 View Details [529..593] PSI-BLAST 81.69897 Structure of CDK2/Cyclin A with PNU-292137


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle