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Protein Overview: gi|65336250

General Information:
Name(s) found: gi|65336250 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|65336250|gb|AAY42392.1| L-type calcium channel alpha-1 subunit [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 2158 amino acids

    Gene Ontology:
    Cellular Component: presynaptic membrane [IDA]
    postsynaptic density [UNKNOWN][IDA]
    caveolar macromolecular signaling complex [UNKNOWN][IEA]
    voltage-gated calcium channel complex [UNKNOWN][IDA][IEA][TAS]
    neuronal cell body [UNKNOWN][IDA]
    plasma membrane [UNKNOWN]
    membrane fraction [UNKNOWN][IDA]
    nucleus [IDA]
    Z disc [IDA]
    T-tubule [IDA]
    dendrite [IDA]
    cytoplasm [UNKNOWN][IEA]
    sarcolemma [IDA]
    dendritic shaft [UNKNOWN][IEA]
    membrane [IEA]
    integral to membrane [UNKNOWN][IEA]
    Biological Process: transmembrane transport [IEA]
    insulin secretion [UNKNOWN][IEA]
    synaptic transmission [UNKNOWN][IEA]
    visual learning [UNKNOWN][IEA]
    regulation of organ growth [UNKNOWN][IEA]
    regulation of blood pressure [UNKNOWN][IEA]
    cellular calcium ion homeostasis [UNKNOWN][IEA]
    elevation of cytosolic calcium ion concentration [UNKNOWN]
    adult walking behavior [UNKNOWN][IEA]
    ion transport [IEA]
    smooth muscle contraction [UNKNOWN][IEA]
    calcium ion transport [UNKNOWN][IEA][IMP]
    glucose homeostasis [UNKNOWN][IEA]
    growth hormone secretion [UNKNOWN][IEA]
    calcium ion-dependent exocytosis [UNKNOWN][IEA]
    smooth muscle contraction involved in micturition [UNKNOWN][IEA]
    regulation of vasoconstriction [UNKNOWN][IEA]
    Molecular Function: ion channel activity [IEA]
    calmodulin binding [UNKNOWN][IEA]
    protein domain specific binding [IPI]
    protein binding [UNKNOWN][IPI]
    voltage-gated ion channel activity [IEA]
    dihydropyridine-sensitive calcium channel activity [UNKNOWN][IEA]
    voltage-gated calcium channel activity [UNKNOWN][IDA][IEA][IMP][TAS]
    protein phosphatase 2A binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCCALDCAC SNYGSPRPAH ANMNANAAAG LAPEHIPTPG AALSWQAAID AARQAKLMGS  60
   61 AGNATISTVS STQRKRQQYG KPKKQGGTTA TRPPRALLCL TLKNPIRRAC ISIVEWKPFE 120
  121 IIILLTIFAN CVALAIYIPF PEDDSNATNS NLERVEYLFL IIFTVEAFLK VIAYGLLFHP 180
  181 NAYLRNGWNL LDFIIVVVGL FSAILEQATK ADGANALGGK GAGFDVKALR AFRVLRPLRL 240
  241 VSGVPSLQVV LNSIIKAMVP LLHIALLVLF VIIIYAIIGL ELFMGKMHKT CYNQEGIIDV 300
  301 PAEEDPSPCA LETGHGRQCQ NGTVCKPGWD GPKHGITNFD NFAFAMLTVF QCITMEGWTD 360
  361 VLYWVNDAVG RDWPWIYFVT LIIIGSFFVL NLVLGVLSGE FSKEREKAKA RGDFQKLREK 420
  421 QQLEEDLKGY LDWITQAEDI DPENEDEGMD EDKPRNRGAP AGLHDQKKGK FAWFSHSTET 480
  481 HVSMPTSETE SVNTENVAGG DIEGENCGAR LAHRISKSKF SRYWRRWNRF CRRKCRAAVK 540
  541 SNVFYWLVIF LVFLNTLTIA SEHYNQPHWL TEVQDTANKA LLALFTAEML LKMYSLGLQA 600
  601 YFVSLFNRFD CFIVCGGILE TILVETKIMS PLGISVLRCV RLLRIFKITR YWNSLSNLVA 660
  661 SLLNSVRSIA SLLLLLFLFI IIFSLLGMQL FGGKFNFDEM QTRRSTFDNF PQSLLTVFQI 720
  721 LTGEDWNSVM YDGIMAYGGP SFPGMLVCIY FIILFICGNY ILLNVFLAIA VDNLADAESL 780
  781 TSAQKEEEEE KERKKLARTA SPEKKQEVME KPAVEESKEE KIELKSITAD GESPPTTKIN 840
  841 MDDLQPSENE DKSPHSNPDT AGEEDEEEPE MPVGPRPRPL SELHLKEKAV PMPEASAFFI 900
  901 FSPNNRFRLQ CHRIVNDTIF TNLILFFILL SSISLAAEDP VQHTSFRNHI LFYFDIVFTT 960
  961 IFTIEIALKM TAYGAFLHKG SFCRNYFNIL DLLVVSVSLI SFGIQSSAIN VVKILRVLRV1020
 1021 LRPLRAINRA KGLKHVVQCV FVAIRTIGNI VIVTTLLQFM FACIGVQLFK GKLYTCSDSS1080
 1081 KQTEAECKGN YITYKDGEVD HPIIQPRSWE NSKFDFDNVL AAMMALFTVS TFEGWPELLY1140
 1141 RSIDSHTEDK GPIYNYRVEI SIFFIIYIII IAFFMMNIFV GFVIVTFQEQ GEQEYKNCEL1200
 1201 DKNQRQCVEY ALKARPLRRY IPKNQHQYKV WYVVNSTYFE YLMFVLILLN TICLAMQHYG1260
 1261 QSCLFKIAMN ILNMLFTGLF TVEMILKLIA FKPKHYFCDA WNTFDALIVV GSIVDIAITE1320
 1321 VHPAEHTQCS PSMSAEENSR ISITFFRLFR VMRLVKLLSR GEGIRTLLWT FIKSFQALPY1380
 1381 VALLIVMLFF IYAVIGMQVF GKIALNDTTE INRNNNFQTF PQAVLLLFRC ATGEAWQDIM1440
 1441 LACMPGKKCA PESEPSNSTE GETPCGSSFA VFYFISFYML CAFLIINLFV AVIMDNFDYL1500
 1501 TRDWSILGPH HLDEFKRIWA EYDPEAKGRI KHLDVVTLLR RIQPPLGFGK LCPHRVACKR1560
 1561 LVSMNMPLNS DGTVMFNATL FALVRTALRI KTEGNLEQAN EELRAIIKKI WKRTSMKLLD1620
 1621 QVVPPAGDDE VTVGKFYATF LIQEYFRKFK KRKEQGLVGK PSQRNALSLQ AGLRTLHDIG1680
 1681 PEIRRAISGD LTAEEELDKA MKEAVSAASE DDIFRRAGGL FGNHVSYYQS DSRSNFPQTF1740
 1741 ATQRPLHINK TGNNQADTES PSHEKLVDST FTPSSYSSTG SNANINNANN TALGRFPHPA1800
 1801 GYSSTVSTVE GHGPPLSPAV RVQEAAWKLS SKRCHSRESQ GATVSQDMFP DETRSSVRLS1860
 1861 EEVEYCSEPS LLSTDILSYQ DDENRQLTCL EEDKREIQPS PKRSFLRSAS LGRRASFHLE1920
 1921 CLKRQKDQGG DISQKTALPL HLVHHQALAV AGLSPLLQRS HSPSTFPRPR PTPPVTPGSR1980
 1981 GRPLQPIPTL RLEGAESSEK LNSSFPSIHC SSWSEETTAC SGGSSMARRA RPVSLTVPSQ2040
 2041 AGAPGRQFHG SASSLVEAVL ISEGLGQFAQ DPKFIEVTTQ ELADACDMTI EEMENAADNI2100
 2101 LSGGAQQSPN GTLLPFVNCR DPGQDRAVVP EDESCVYALG RGRSEEALPD SRSYVSNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle