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Protein Overview: NAAT1-PA

General Information:
Name(s) found: NAAT1-PA / FBpp0070763 [FlyBase]
Description(s) found:
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  • gi|30913427|sp|Q9W4C5.2|Y252_DROME RecName: Full=Uncharacterized sodium-dependent transporter CG3252 [NCBI NR]
  • gi|24639853|ref|NP_572219.1| CG3252 [Drosophila melanogaster] [NCBI NR]
  • gi|22831734|gb|AAF46031.2| CG3252 [Drosophila melanogaster] [NCBI NR]
  • Uncharacterized sodium-dependent transporter CG3252 OS=Drosophila melanogaster GN=CG3252 PE=1 SV=2 [Swiss-Prot]
  • Sodium-dependent nutrient amino acid transporter 1 OS=Drosophila melanogaster GN=NAAT1 PE=1 SV=2 [Swiss-Prot]
  • The gene Nutrient Amino Acid Transporter 1 is referred to in FlyBase by the symbol Dmel\NAAT1 (CG3252, FBgn0029762). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5299265..5304878. It has the cytological map location 4F9. There is experimental evidence that it has the molecular function</span>: L-amino acid transmembrane transporter activity; D-amino acid transmembrane transporter activity; neutral amino acid transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: D-amino acid transport; neutral amino acid transport; L-amino acid transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3252-PA translation from_gene[CG3252 CG3252 FBgn0029762] seq_release:3 mol_weight=71762 cds_boundaries:(X:5,146,131..5,151,180[-]) aa_length:641 transcript_info:[CG3252-RA seq_release:3] gene_info:[gene symbol:CG3252 FBgn0029762 gene_boundaries:(X:5 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W4C5) Hypothetical sodium-dependent transporter CG3252 [DrosMelano7227.FASTAC.txt]
  • CG3252-PA [Drosophila melanogaster]gi|24639853|ref|NP_572219.1| CG3252-PA [Drosophila melanogaster]gi|30913427|sp|Q9W4C5|Y252_DROME Hypothetical sodium-dependent transporter CG3252 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(5299547..5299723,5299790..5299884,5299938..5300114,5300182..5300281,5300359..5301100,5301353..5301725,5301780..5301960,5304519..5304599); ID=FBpp0070763; name=CG3252-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp007 [fly-100309-contam.fasta]
  • CG3252-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Hypothetical sodium-dependent transporter CG3252 [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(5299547..5299723,5299790..5299884,5299938..5300114,5300182..5300281,5300359..5301100,5301353..5301725,5301780..5301960,5304519..5304599); ID=FBpp0070763; name=CG3252-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(5299547..5299723,5299790..5299884,5299938..5300114,5300182..5300281,5300359..5301100,5301353..5301725,5301780..5301960,5304519..5304599); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Transporter OS=Drosophila melanogaster GN=CG3252-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(5299547..5299723,5299790..5299884,5299938..5300114,5300182..5300281,5300359..5301100,5301353..5301725,5301780..5301960,5304519..5304599); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031,FlyMine:FBpp0070763,modMine:FBpp0070763; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(5410486..5410566,5407747..5407927,5407320..5407692,5406326..5407067,5406149..5406248,5405905..5406081,5405757..5405851,5405514..5405690)); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031,FlyMine:FBpp0070763,modMine:FBpp0070763; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(5410486..5410566,5407747..5407927,5407320..5407692,5406326..5407067,5406149..5406248,5405905..5406081,5405757..5405851,5405514..5405690)); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031,FlyMine:FBpp0070763,modMine:FBpp0070763; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0070763 type=protein; loc=X:complement(join(5410486..5410566,5407747..5407927,5407320..5407692,5406326..5407067,5406149..5406248,5405905..5406081,5405757..5405851,5405514..5405690)); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031,FlyMine:FBpp0070763,modMine:FBpp0070763; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(5410486..5410566,5407747..5407927,5407320..5407692,5406326..5407067,5406149..5406248,5405905..5406081,5405757..5405851,5405514..5405690)); ID=FBpp0070763; name=NAAT1-PA; parent=FBgn0029762,FBtr0070797; dbxref=FlyBase:FBpp0070763,FlyBase_Annotation_IDs:CG3252-PA,GB_protein:AAF46031.2,REFSEQ:NP_572219,GB_protein:AAF46031,UniProt/Swiss-Prot:Q9W4C5,FlyMine:FBpp0070763,modMine:FBpp0070763; MD5=282c08aa9cdc2753703335a76cc9ae0c; length=641; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 641 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEA]
    integral to membrane [NAS]
    Biological Process: sodium ion transport [NAS]
    neurotransmitter transport [ISS][NAS]
    L-amino acid transport [IDA]
    neutral amino acid transport [IDA]
    D-amino acid transport [IDA]
    Molecular Function: D-amino acid transmembrane transporter activity [IDA]
    neurotransmitter transporter activity [ISS]
    L-amino acid transmembrane transporter activity [IDA]
    neurotransmitter:sodium symporter activity [IEA][NAS]
    neutral amino acid transmembrane transporter activity [IDA]
    potassium:amino acid symporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELKGVQPSN GSSNGSGNGA TNAASTEKTD AEKPTAERTN WGNGLEFLMS CISVSVGLGN  60
   61 VWRFPFTAYE NGGGAFLIPY IIVLFLIGKP MYYLEMIMGQ FTSQGTVKIW SVVPGFVGVG 120
  121 YGQAFGTICI ISYYSSLLAL TLYYLFVSFQ SELPWSYCRD EWTNCVNSRP QEYVDNLLTG 180
  181 VSLANESARN LSGIVANDET EKLQSSSELY FLNVVIKEKL DISDGVGDPD WKLTLALFVA 240
  241 WVVIFLVIMR GVKSSGKAAY FLALFPYVVL FVLLIRAVTL EGARDGILFF LEPQWGELLN 300
  301 PTVWKEAVVQ CFFSLAVGSG PIIMFASYNR FDHGIYRDAM IVTTLDTLTS LLGGITIFAI 360
  361 LGNLAHNLQI ENIRDVVRSG TGLAFISYPD AISKFQAVPQ LFSVLFFFML FVLGIGSIVA 420
  421 LQSTIVTIIC DQFKGWKYWK VALTTSVCGF LMGLVYVTPG GQWILTLVDF YGGTYVVFIL 480
  481 AIFELAGIVW VYGLQNFCDD IEFMCNRRVS LYWRVCWSFF TPVMMIIIFI YSMVTIEPIK 540
  541 YSELYFPEAA NIAGWLLFAI GAAQFPLWGL WYISRHPQGT YWKSLKASLK PSDRWGPANP 600
  601 EIRREWVIFK NQKAAQRATQ KDTSKLGFFW RKVANFCGSN K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..576] PSI-BLAST 53.69897 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
    2 View Details [577..641] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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