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Protein Overview: rpr-PA

General Information:
Name(s) found: rpr-PA / FBpp0074886 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene reaper is referred to in FlyBase by the symbol Dmel\rpr (CG4319, FBgn0011706). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18390653..18391503. It has the cytological map location 75C6. There is experimental evidence that it has the molecular function</span>: phospholipid binding. There is experimental evidence that it is involved in the biological process</span>: apoptosis; induction of apoptosis; programmed cell death; ecdysone-mediated induction of salivary gland cell autophagic cell death; regulation of protein catabolic process; larval midgut cell programmed cell death; salivary gland cell autophagic cell death; cell death. 67 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; adult segment; nervous system; peripheral nervous system; external compound sense organ; embryonic nervous system; endocrine system; female germline cyst; embryonic neuron; adult mesothoracic segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 65 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TAS]
    mitochondrion [IDA]
    mitochondrial outer membrane [IDA]
    Biological Process: larval midgut cell programmed cell death [IGI][NAS]
    regulation of proteolysis [TAS]
    regulation of protein catabolic process [IDA]
    salivary gland cell autophagic cell death [IGI][NAS]
    [NOT]nurse cell apoptosis [TAS]
    ecdysone-mediated induction of salivary gland cell autophagic cell death [IEP][NAS]
    larval central nervous system remodeling [TAS]
    response to DNA damage stimulus [TAS]
    induction of apoptosis by ionic changes [TAS]
    cell death [IMP]
    embryonic development via the syncytial blastoderm [TAS]
    induction of apoptosis [IGI][NAS][TAS]
    apoptosis [IEP][IGI][IMP][NAS][TAS]
    programmed cell death [IMP][TAS]
    negative regulation of translation [TAS]
    protein ubiquitination [TAS]
    Molecular Function: phospholipid binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVAFYIPDQ ATLLREAEQK EQQILRLRES QWRFLATVVL ETLRQYTSCH PKTGRKSGKY  60
   61 RKPSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..65] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle