Protein Overview: ABCB7-PC

General Information:
Name(s) found:	ABCB7-PC / FBpp0072639 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7292114\|gb\|AAF47526.1\| CG7955, isoform C [Drosophila melanogaster] [NCBI NR] gi\|21357851\|ref\|NP_647634.1\| CG7955, isoform C [Drosophila melanogaster] [NCBI NR] gi\|15291423\|gb\|AAK92980.1\| GH20617p [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\ABCB7 (CG7955, FBgn0035244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1618392..1623413. It has the cytological map location 62A8-62A9. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled to transmembrane movement of substances; transporter activity; heme transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: heme transport; iron-sulfur cluster assembly. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] >CG7955-PC translation from_gene[CG7955 CG7955 FBgn0035244] seq_release:3 mol_weight=66105 cds_boundaries:(3L:1,601,613..1,603,615[+]) aa_length:606 transcript_info:[CG7955-RC seq_release:3] gene_info:[gene symbol:CG7955 FBgn0035244 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta] >CG7955-PB translation from_gene[CG7955 CG7955 FBgn0035244] seq_release:3 mol_weight=66105 cds_boundaries:(3L:1,601,613..1,603,615[+]) aa_length:606 transcript_info:[CG7955-RB seq_release:3] gene_info:[gene symbol:CG7955 FBgn0035244 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta] >CG7955-PA translation from_gene[CG7955 CG7955 FBgn0035244] seq_release:3 mol_weight=66105 cds_boundaries:(3L:1,601,613..1,603,615[+]) aa_length:606 transcript_info:[CG7955-RA seq_release:3] gene_info:[gene symbol:CG7955 FBgn0035244 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta] (Q9W0C5) CG7955 protein (GH20617P) [DrosMelano7227.FASTAC.txt] (AAF47526) CG7955-PC [DrosMelano7227.FASTAC.txt] (AE003472) CG7955 gene product [alt 3] [Drosophila melanogaster] [yeastflysequest.fasta] (AE003472) CG7955 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta] CG7955-PC, isoform C [Drosophila melanogaster]gi\|15291423\|gb\|AAK92980.1\| GH20617p [Drosophila melanogaster]gi\|21357851\|ref\|NP_647634.1\| CG7955-PC [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(1620984..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072639; name=CG7955-PC; parent=FBgn0035244,FBtr0072756; dbxref=FlyBase:FBpp0072639,FlyBase_Annotation_IDs:CG7955-PC,GB_protein:AAF47526.1,REFSEQ:NP_647 [fly-100309-contam.fasta] GH20617p [Drosophila melanogaster] [nr-271106-contam.fasta] CG7955-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(1620984..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072639; name=CG7955-PC; parent=FBgn0035244,FBtr0072756; dbxref=FlyBase:FBpp0072639,FlyBase_Annotation_IDs:CG7955-PC,GB_protein:AAF47526.1,REFSEQ:NP_647634,GB_protein:AAF47526; MD5=b1fe2808bacb87f58860acc13b5da4fd; length=606; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(1620984..1621042,1621103..1621257,1621317..1622665,1622732..1622989); ID=FBpp0072639; name=ABCB7-PC; parent=FBgn0035244,FBtr0072756; dbxref=FlyBase:FBpp0072639,FlyBase_Annotation_IDs:CG7955-PC,GB_protein:AAF47526.1,REFSEQ:NP_647634,GB_protein:AAF47526; MD5=b1fe2808bacb87f58860acc13b5da4fd; length=606; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] ABCB7, isoform C OS=Drosophila melanogaster GN=ABCB7 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	606 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] ATP-binding cassette (ABC) transporter complex [ISS] mitochondrial inner membrane [ISS]
Biological Process:	transmembrane transport [IEA] heme transport [ISS] iron-sulfur cluster assembly [ISS]
Molecular Function:	ATP binding [IEA] ATPase activity, coupled to transmembrane movement of substances [ISS] heme transporter activity [ISS] transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRAMMAYIW PKEDPLVRKR VGISLGLLAG SKLLTVCVPF LFKGAVDTMT TLNMDTAPDA  60
   61 VLSAATALML GYGIARASAA GFNELRNAVF AKVAHHSIRK IASNVFLHLH NLDLAFHLNK 120
  121 QTGALSKTID RGSRGINFVL SAMVFNIVPT IFELALVSSI LGVKCGLAFA GVSMGCVGIY 180
  181 AAYTLSVTQW RTQFRVFMNQ AENEAGNKAV DSLINYETVK YFNNEKYEAG CYNEVLKKYE 240
  241 AASLKTSSSL ALLNFGQNAI FSSALSLIMV LAAKEIAQGN MTVGDLVMVN ALLFQLSIPL 300
  301 GFLGSVYREV RQALLDMRAM FTLMNVDSSI QTAANAQPLF VDTTNSSIEF RNVSFEYEPG 360
  361 KPIFRDLSFT IPAGKNVAIV GGSGSGKSSM VRLLFRFFEP NSGKVLIGGQ DISAVDLESL 420
  421 RKVIAVVPQD SVLFHNTIEH NIHYGNLSKS HAEVQNAARM ADLHDSIMSW PGQYSTQVGE 480
  481 RGLKLSGGEK QRVAIARAIL KNTPILIFDE ATSSLDSITE HNILQALTRA TSGRTSICIA 540
  541 HRLSTVKDAD EILVLENGRV GERGTHSELL RQNGLYARLW ETQTQQFDPS REINEEVAAK 600
  601 KTRGVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ABCB7-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: